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The initial reports onantigenicity were based on observations with an early preparation of onaboulinumtoxinA(1979 Botox®) that reported an antibody rate of 4% to 10% in patients being treated forcervical dystonia. Idiopathic colonic inertiacommonly affects young females. In the absence of ovarian hormonestimulation, the secretory cells of the TDLUs degenerate anddisappear, leaving only ducts to create a histologic pattern thatresembles that ofmale breast. (1997) The effects of music therapy oninteractions between family caregivers and their care receiverswith late stage dementia.
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